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Effector domain of human Dlg tumor suppressor acts as a switch that relieves auto-inhibition of kinesin-3 motor GAKIN/KIF13B
Activity of motor proteins must be tightly regulated in the cells, in order to prevent unnecessary energy consumption and to maintain proper distribution of cellular components. Loading of the cargo molecule is one likely mechanism to activate an inactive motor. Here, we report that the activity of...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525504/ https://ncbi.nlm.nih.gov/pubmed/17696365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701169w |
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