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Effector domain of human Dlg tumor suppressor acts as a switch that relieves auto-inhibition of kinesin-3 motor GAKIN/KIF13B

Activity of motor proteins must be tightly regulated in the cells, in order to prevent unnecessary energy consumption and to maintain proper distribution of cellular components. Loading of the cargo molecule is one likely mechanism to activate an inactive motor. Here, we report that the activity of...

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Detalhes bibliográficos
Main Authors: Yamada, Kaori H., Hanada, Toshihiko, Chishti, Athar H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525504/
https://ncbi.nlm.nih.gov/pubmed/17696365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701169w
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