The NALP3/Cryopyrin-Inflammasome Complex is Expressed in LPS-Induced Ocular Inflammation

In the inflammosome complex, NALP3 or NALP1 binds to ASC and activates caspase-1 which induces IL-1β. In murine LPS-induced ocular inflammation, the production of IL-1β is increased. We suggest that NALP3- or NALP1-inflammasome complex can be participating in the LPS-induced ocular inflammation. In...

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Bibliographische Detailangaben
Hauptverfasser: González-Benítez, José F., Juárez-Verdayes, Marco A., Rodríguez-Martínez, Sandra, Cancino-Diaz, Mario E., García-Vázquez, Francisco, Cancino-Diaz, Juan C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522304/
https://ncbi.nlm.nih.gov/pubmed/18769497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/614345
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