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Taxol Suppresses Dynamics of Individual Microtubules in Living Human Tumor Cells

Microtubules are intrinsically dynamic polymers, and their dynamics play a crucial role in mitotic spindle assembly, the mitotic checkpoint, and chromosome movement. We hypothesized that, in living cells, suppression of microtubule dynamics is responsible for the ability of taxol to inhibit mitotic...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Principais autores: Yvon, Anne-Marie C., Wadsworth, Patricia, Jordan, Mary Ann
Format: Artigo
Jezik:Inglês
Izdano: American Society for Cell Biology 1999
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10198049/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.4.947
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