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Taxol Suppresses Dynamics of Individual Microtubules in Living Human Tumor Cells

Microtubules are intrinsically dynamic polymers, and their dynamics play a crucial role in mitotic spindle assembly, the mitotic checkpoint, and chromosome movement. We hypothesized that, in living cells, suppression of microtubule dynamics is responsible for the ability of taxol to inhibit mitotic...

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Detalhes bibliográficos
Main Authors: Yvon, Anne-Marie C., Wadsworth, Patricia, Jordan, Mary Ann
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25218/
https://ncbi.nlm.nih.gov/pubmed/10198049
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