Effect of Structural and Stereochemical Methylproline Isomers on Actinomycin Biosynthesis
The inhibitory effect of methylprolines on actinomycin biosynthesis by Streptomyces antibioticus was studied; the order of effectiveness was 3- >4- >5-methyl-dl-proline. Cis-3-methyl-dl-proline was 14 times more active than the trans isomer. It was also found that 4- and, possibly, 5-methylproline w...
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| Publicado en: | J Bacteriol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1968
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252115/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4171116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.95.3.952-958.1968 |
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