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Effect of Structural and Stereochemical Methylproline Isomers on Actinomycin Biosynthesis

The inhibitory effect of methylprolines on actinomycin biosynthesis by Streptomyces antibioticus was studied; the order of effectiveness was 3- >4- >5-methyl-dl-proline. Cis-3-methyl-dl-proline was 14 times more active than the trans isomer. It was also found that 4- and, possibly, 5-methylpro...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Yoshida, Tadashi, Mauger, Anthony, Weissbach, Herbert, Katz, Edward
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1968
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC252115/
https://ncbi.nlm.nih.gov/pubmed/4171116
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