Llwytho...

Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity

Adaptation of avian influenza viruses for replication and transmission in the human host is believed to require mutations in the hemagglutinin glycoprotein (HA) which enable binding to human α2-6 sialosides and concomitant reduction in affinity for avian α2-3 linked sialosides. Here, we show by glyc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stevens, James, Blixt, Ola, Chen, Li-Mei, Donis, Ruben O., Paulson, James C., Wilson, Ian A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519951/
https://ncbi.nlm.nih.gov/pubmed/18672252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.04.016
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