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Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity
Adaptation of avian influenza viruses for replication and transmission in the human host is believed to require mutations in the hemagglutinin glycoprotein (HA) which enable binding to human α2-6 sialosides and concomitant reduction in affinity for avian α2-3 linked sialosides. Here, we show by glyc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519951/ https://ncbi.nlm.nih.gov/pubmed/18672252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.04.016 |
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