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Cultured rat hepatocytes upregulate Akt and ERK in an ErbB-2-dependent manner
Epidermal growth factor (EGF) stimulates freshly plated adult hepatocytes to synthesize DNA, but only after they pass through a lag phase of 40 h following EGF exposure. The longer the cells are maintained, they become more responsive to EGF and the lag phase shortens. Maximal EGF-mediated stimulati...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519852/ https://ncbi.nlm.nih.gov/pubmed/18535289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00597.2007 |
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