Polyubiquitination of Prolactin Receptor Stimulates Its Internalization, Postinternalization Sorting, and Degradation via the Lysosomal Pathway

The ubiquitination of the receptor that mediates signaling induced by the polypeptide pituitary hormone prolactin (PRL) has been shown to lead to the degradation of this receptor and to the ensuing negative regulation of cellular responses to PRL. However, the mechanisms of PRL receptor (PRLr) prote...

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Asıl Yazarlar: Varghese, Bentley, Barriere, Herve, Carbone, Christopher J., Banerjee, Anamika, Swaminathan, Gayathri, Plotnikov, Alexander, Xu, Ping, Peng, Junmin, Goffin, Vincent, Lukacs, Gergely L., Fuchs, Serge Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519723/
https://ncbi.nlm.nih.gov/pubmed/18573876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00350-08
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