A Replication-Competent, Neuronal Spread-Defective, Live Attenuated Herpes Simplex Virus Type 1 Vaccine

Herpes simplex virus type 1 (HSV-1) produces oral lesions, encephalitis, keratitis, and severe infections in the immunocompromised host. HSV-1 is almost as common as HSV-2 in causing first episodes of genital herpes, a disease that is associated with an increased risk of human immunodeficiency virus...

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Bibliografiske detaljer
Main Authors: Brittle, Elizabeth E., Wang, Fushan, Lubinski, John M., Bunte, Ralph M., Friedman, Harvey M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519657/
https://ncbi.nlm.nih.gov/pubmed/18562543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00551-08
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