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Small-Molecule Inhibitor Which Reactivates p53 in Human T-Cell Leukemia Virus Type 1-Transformed Cells

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of the aggressive and fatal disease adult T-cell leukemia. Previous studies have demonstrated that the HTLV-1-encoded Tax protein inhibits the function of tumor suppressor p53 through a Tax-induced NF-κB pathway. Given these attribut...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jung, Kyung-Jin, Dasgupta, Arindam, Huang, Keven, Jeong, Soo-Jin, Pise-Masison, Cynthia, Gurova, Katerina V., Brady, John N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519633/
https://ncbi.nlm.nih.gov/pubmed/18550670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00690-08
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