Disparity between Levels of In Vitro Neutralization of Vaccinia Virus by Antibody to the A27 Protein and Protection of Mice against Intranasal Challenge

Immunization with recombinant proteins may provide a safer alternative to live vaccinia virus for prophylaxis of poxvirus infections. Although antibody protects against vaccinia virus infection, the mechanism is not understood and the selection of immunogens is daunting as there are dozens of surfac...

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Bibliographic Details
Main Authors: Fogg, Christiana N., Americo, Jeffrey L., Earl, Patricia L., Resch, Wolfgang, Aldaz-Carroll, Lydia, Eisenberg, Roselyn J., Cohen, Gary H., Moss, Bernard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519570/
https://ncbi.nlm.nih.gov/pubmed/18524827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00568-08
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