Major Neutralizing Sites on Vaccinia Virus Glycoprotein B5 Are Exposed Differently on Variola Virus Ortholog B6

Immunization against smallpox (variola virus) with Dryvax, a live vaccinia virus (VV), was effective, but now safety is a major concern. To overcome this issue, subunit vaccines composed of VV envelope proteins from both forms of infectious virions, including the extracellular enveloped virion (EV)...

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Bibliographische Detailangaben
Hauptverfasser: Aldaz-Carroll, Lydia, Xiao, Yuhong, Whitbeck, J. Charles, de Leon, Manuel Ponce, Lou, Huan, Kim, Mikyung, Yu, Jessica, Reinherz, Ellis L., Isaacs, Stuart N., Eisenberg, Roselyn J., Cohen, Gary H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951295/
https://ncbi.nlm.nih.gov/pubmed/17522205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00374-07
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