A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost

The heightened concern about the intentional release of variola virus has led to the need to develop safer smallpox vaccines. While subunit vaccine strategies are safer than live virus vaccines, subunit vaccines have been hampered by the need for multiple boosts to confer optimal protection. Here we...

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Main Authors: Xiao, Yuhong, Aldaz-Carroll, Lydia, Ortiz, Alexandra M., Whitbeck, J. Charles, Alexander, Edward, Lou, Huan, Davis, J. Heather L., Braciale, Thomas J., Eisenberg, Roselyn J., Cohen, Gary H., Isaacs, Stuart N.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857298/
https://ncbi.nlm.nih.gov/pubmed/17098336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.10.009
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