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The Secondary Structure of the Human Immunodeficiency Virus Type 1 Transcript Modulates Viral Splicing and Infectivity

Splicing of human immunodeficiency virus type 1 (HIV-1) exon 6D is regulated by the presence of a complex splicing regulatory element (SRE) sequence that interacts with the splicing factors hnRNP H and SC35. In this work, we show that, in the context of the wild-type viral sequence, hnRNP H acts as...

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Bibliografiske detaljer
Main Authors: Jablonski, Joseph A., Buratti, Emanuele, Stuani, Cristiana, Caputi, Massimo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519558/
https://ncbi.nlm.nih.gov/pubmed/18550660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00721-08
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