Murine Leukemia Virus Uses NXF1 for Nuclear Export of Spliced and Unspliced Viral Transcripts

Intron-containing mRNAs are subject to restricted nuclear export in higher eukaryotes. Retroviral replication requires the nucleocytoplasmic transport of both spliced and unspliced RNA transcripts, and RNA export mechanisms of gammaretroviruses are poorly characterized. Here, we report the involveme...

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Autores principales: Sakuma, Toshie, Davila, Jaime I., Malcolm, Jessica A., Kocher, Jean-Pierre A., Tonne, Jason M., Ikeda, Yasuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993726/
https://ncbi.nlm.nih.gov/pubmed/24478440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03584-13
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