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Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice

Heterozygous bone morphogenetic protein receptor-II-knockout (BMPR2(+/−)) mice have a similar genetic trait like that in some idiopathic pulmonary arterial hypertension patients. To examine the effect of pulmonary endothelial injury in BMPR2(+/−) mice, we challenged the mice with two injections of m...

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Autori principali: Song, Yanli, Coleman, Laura, Shi, Jianru, Beppu, Hideyuki, Sato, Kaori, Walsh, Kenneth, Loscalzo, Joseph, Zhang, Ying-Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519229/
https://ncbi.nlm.nih.gov/pubmed/18552156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.91519.2007
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