Cryo-electron microscopy reveals a novel DNA-binding site on the MCM helicase

The eukaryotic MCM2–7 complex is recruited at origins of replication during the G1 phase and acts as the main helicase at the replication fork during the S phase of the cell cycle. To characterize the interplay between the MCM helicase and DNA prior to the melting of the double helix, we determined...

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Detaylı Bibliyografya
Asıl Yazarlar: Costa, Alessandro, van Duinen, Gijs, Medagli, Barbara, Chong, James, Sakakibara, Nozomi, Kelman, Zvi, Nair, Satish K, Patwardhan, Ardan, Onesti, Silvia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519097/
https://ncbi.nlm.nih.gov/pubmed/18650940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.135
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