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Paclitaxel loading in PLGA nanospheres affected the in vitro drug cell accumulation and antiproliferative activity
BACKGROUND: PTX is one of the most widely used drug in oncology due to its high efficacy against solid tumors and several hematological cancers. PTX is administered in a formulation containing 1:1 Cremophor(® )EL (polyethoxylated castor oil) and ethanol, often responsible for toxic effects. Its enca...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519087/ https://ncbi.nlm.nih.gov/pubmed/18657273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-212 |
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