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Differential regulation of the yeast isozymes of pyruvate carboxylase and the locus of action of acetyl CoA.

Unlike other eukaryotes studied to date, yeast has two genes for pyruvate carboxylase coding for very similar, but not identical, isozymes (Pyc1 and Pyc2), both of which are located in the cytoplasm. We have found that there are marked differences in the kinetic properties of the isozymes potentiall...

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Autori principali: Jitrapakdee, Sarawut, Adina-Zada, Abdussalam, Besant, Paul G., Surinya, Kathy H., Cleland, W. Wallace, Wallace, John C., Attwood, Paul V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519008/
https://ncbi.nlm.nih.gov/pubmed/17478118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2007.03.016
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