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Mutations at Phosphorylation Sites of Xenopus Microtubule-associated Protein 4 Affect Its Microtubule-binding Ability and Chromosome Movement during Mitosis

Microtubule-associated proteins (MAPs) bind to and stabilize microtubules (MTs) both in vitro and in vivo and are thought to regulate MT dynamics during the cell cycle. It is known that p220, a major MAP of Xenopus, is phosphorylated by p34(cdc2) kinase as well as MAP kinase in mitotic cells, and th...

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Bibliographic Details
Main Authors: Shiina, Nobuyuki, Tsukita, Shoichiro
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25190/
https://ncbi.nlm.nih.gov/pubmed/10069806
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