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Adenomatous Polyposis Coli (APC) Protein Moves along Microtubules and Concentrates at Their Growing Ends in Epithelial Cells

Adenomatous polyposis coli (APC) tumor suppressor protein has been shown to be localized near the distal ends of microtubules (MTs) at the edges of migrating cells. We expressed green fluorescent protein (GFP)-fusion proteins with full-length and deletion mutants of Xenopus APC in Xenopus epithelial...

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Main Authors: Mimori-Kiyosue, Yuko, Shiina, Nobuyuki, Tsukita, Shoichiro
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174811/
https://ncbi.nlm.nih.gov/pubmed/10662776
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