Microtubule detyrosination guides chromosomes during mitosis

Before chromosomes segregate into daughter cells they align at the mitotic spindle equator, a process known as chromosome congression. CENP-E/Kinesin-7 is a microtubule plus-end-directed kinetochore motor required for congression of pole-proximal chromosomes. Because the plus-ends of many astral mic...

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Udgivet i:Science
Main Authors: Barisic, Marin, Silva e Sousa, Ricardo, Tripathy, Suvranta K., Magiera, Maria M., Zaytsev, Anatoly V., Pereira, Ana L., Janke, Carsten, Grishchuk, Ekaterina L., Maiato, Helder
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506776/
https://ncbi.nlm.nih.gov/pubmed/25908662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa5175
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