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A Unique Insert of Leucyl-tRNA Synthetase is Required for Aminoacylation and Not Amino Acid Editing

Leucyl-tRNA synthetase (LeuRS) is a class I enzyme, which houses its aminoacylation active site in a canonical core that is defined by a Rossmann nucleotide binding fold. In addition, many LeuRSs bear a unique polypeptide insert comprised of about 50 amino acids located just upstream of the conserve...

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Main Authors: Vu, Michael T., Martinis, Susan A.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518912/
https://ncbi.nlm.nih.gov/pubmed/17407263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062078j
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