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Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos

The importance of Notch signaling pathway in the regulation of vascular development and angiogenesis is suggested by the expression of Notch receptors and ligands in vascular endothelial cells (ECs) and the observed vascular phenotypes in mutants of Notch receptors or ligands, especially Dll4. DLL4...

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Autors principals: Trindade, Alexandre, Ram Kumar, S., Scehnet, Jeffrey S., Lopes-da-Costa, Luis, Becker, Jorg, Jiang, Weidong, Liu, Ren, Gill, Parkash S., Duarte, Antonio
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518882/
https://ncbi.nlm.nih.gov/pubmed/18559979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-112748
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