Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion

Vascular development is dependent on various growth factors and certain modifiers critical for providing arterial or venous identity, interaction with the surrounding stroma and tissues, hierarchic network formation, and recruitment of pericytes. Notch receptors and ligands (Jagged and Delta-like) p...

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Main Authors: Scehnet, Jeffrey S., Jiang, Weidong, Ram Kumar, S., Krasnoperov, Valery, Trindade, Alexandre, Benedito, Rui, Djokovic, Dusan, Borges, Cristina, Ley, Eric J., Duarte, Antonio, Gill, Parkash S.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Hemostasis, Thrombosis, and Vascular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885521/
https://ncbi.nlm.nih.gov/pubmed/17311993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-12-063933
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