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Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation

Mechanosensing followed by mechanoresponses by cells is well established, but the mechanisms by which mechanical force is converted into biochemical events are poorly understood. Vascular endothelial cells (ECs) exhibit flow- and stretch-dependent responses and are widely used as a model for studyin...

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Detalhes bibliográficos
Main Authors: Chiu, Yi-Jen, McBeath, Elena, Fujiwara, Keigi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518713/
https://ncbi.nlm.nih.gov/pubmed/18710921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801062
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