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Poleward transport of Eg5 by dynein–dynactin in Xenopus laevis egg extract spindles

Molecular motors are required for spindle assembly and maintenance during cell division. How motors move and interact inside spindles is unknown. Using photoactivation and photobleaching, we measure mitotic motor movement inside a dynamic spindle. We find that dynein–dynactin transports the essentia...

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Bibliografiske detaljer
Main Authors: Uteng, Marianne, Hentrich, Christian, Miura, Kota, Bieling, Peter, Surrey, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518710/
https://ncbi.nlm.nih.gov/pubmed/18710923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801125
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