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Impact of Diabetes Susceptibility Loci on Progression From Pre-Diabetes to Diabetes in At-Risk Individuals of the Diabetes Prevention Trial–Type 1 (DPT-1)

OBJECTIVE—The unfolding of type 1 diabetes involves a number of steps: defective immunological tolerance, priming of anti-islet autoimmunity, and destruction of insulin-producing β-cells. A number of genetic loci contribute to susceptibility to type 1 diabetes, but it is unclear which stages of the...

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Hlavní autoři: Butty, Vincent, Campbell, Christopher, Mathis, Diane, Benoist, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518486/
https://ncbi.nlm.nih.gov/pubmed/18556337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1736
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