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Using leucine zipper to facilitate α-synuclein assembly

The accumulation of filamentous α-synuclein (α-S) is associated with Parkinson’s disease. It remains controversial as to the mode (antiparallel or parallel) of α-S self-assembly and whether an exact alignment of the central hydrophobic region is essential. In the present study, we performed in vitro...

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Detalhes bibliográficos
Main Authors: Jiang, Peizhou, Ko, Li-wen, Jansen, Karen R., Golde, Todd E., Yen, Shu-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518257/
https://ncbi.nlm.nih.gov/pubmed/18492724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-108365
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