CHEK2 Mutations Affecting Kinase Activity Together With Mutations in TP53 Indicate a Functional Pathway Associated with Resistance to Epirubicin in Primary Breast Cancer

BACKGROUND: Chemoresistance is the main obstacle to cure in most malignant diseases. Anthracyclines are among the main drugs used for breast cancer therapy and in many other malignant conditions. Single parameter analysis or global gene expression profiles have failed to identify mechanisms causing...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chrisanthar, Ranjan, Knappskog, Stian, Løkkevik, Erik, Anker, Gun, Østenstad, Bjørn, Lundgren, Steinar, Berge, Elisabet O., Risberg, Terje, Mjaaland, Ingvil, Mæhle, Lovise, Engebretsen, Lars Fredrik, Lillehaug, Johan Richard, Lønning, Per Eystein
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2008
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518116/
https://ncbi.nlm.nih.gov/pubmed/18725978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003062
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia