Genetic Variability of Hepatitis C Virus before and after Combined Therapy of Interferon plus Ribavirin

We present an analysis of the selective forces acting on two hepatitis C virus genome regions previously postulated to be involved in the viral response to combined antiviral therapy. One includes the three hypervariable regions in the envelope E2 glycoprotein, and the other encompasses the PKR bind...

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Detalhes bibliográficos
Main Authors: Cuevas, José Manuel, Torres-Puente, Manuela, Jiménez-Hernández, Nuria, Bracho, María Alma, García-Robles, Inmaculada, Wrobel, Boris, Carnicer, Fernando, del Olmo, Juan, Ortega, Enrique, Moya, Andrés, González-Candelas, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518109/
https://ncbi.nlm.nih.gov/pubmed/18725975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003058
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