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A role for the cyclin box in the ubiquitin-mediated degradation of cyclin G1

Cyclin G1 was identified as a transcriptional target of p53 that encodes a protein with strong homology to the cyclin family of cell cycle regulators. We show that either ectopically expressed or endogenous cyclin G1 protein is very unstable, undergoes modification with ubiquitin and is likely degra...

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Detalhes bibliográficos
Main Authors: Piscopo, Denise M., Hinds, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518098/
https://ncbi.nlm.nih.gov/pubmed/18632610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6346
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