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Antibody induced injury to podocytes with proteinuria and foot process swelling in a transgenic (T16) mouse
T16 mice contain a human 3′ untranslated sequence of the Thy 1.1 gene. Unlike normal mice they express Thy 1.1 protein on the podocytes which was immuno-localized to podocyte apical and basal plasma membranes and filtration slit. When monoclonal anti-Thy 1.1 antibody (OX7) was injected in nonprotein...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
1999
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517763/ https://ncbi.nlm.nih.gov/pubmed/10469262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.1999.00098.x |
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