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B cell–derived IL-4 acts on podocytes to induce proteinuria and foot process effacement
The efficacy of B cell depletion therapies in diseases such as nephrotic syndrome and rheumatoid arthritis suggests a broader role in B cells in human disease than previously recognized. In some of these diseases, such as the minimal change disease subtype of nephrotic syndrome, pathogenic antibodie...
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| Опубликовано в: : | JCI Insight |
|---|---|
| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752294/ https://ncbi.nlm.nih.gov/pubmed/29093269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.81836 |
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