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Rac1 Activation in Podocytes Induces Rapid Foot Process Effacement and Proteinuria

The kidney's vital filtration function depends on the structural integrity of the glomerulus, the proximal portion of the nephron. Within the glomerulus, the architecturally complex podocyte forms the final cellular barrier to filtration. Injury to the podocyte results in a morphological change...

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Detalhes bibliográficos
Main Authors: Yu, Haiyang, Suleiman, Hani, Kim, Alfred H. J., Miner, Jeffrey H., Dani, Adish, Shaw, Andrey S., Akilesh, Shreeram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838009/
https://ncbi.nlm.nih.gov/pubmed/24061480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00730-13
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