Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor-β-binding protein-1

Mice lacking aryl hydrocarbon (dioxin) receptor (AhR) had variable degree of hepatic fibrosis and altered liver architecture. Transforming growth factor-β (TGF-β), a major profibrogenic molecule in the liver, is localized to the extracellular matrix by its association to the latent TGF-β-binding pro...

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Detalhes bibliográficos
Main Authors: Corchero, Javier, Martín-Partido, Gervasio, Dallas, Sarah L, Fernández-Salguero, Pedro M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517523/
https://ncbi.nlm.nih.gov/pubmed/15379962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0959-9673.2004.00397.x
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