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Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor-β-binding protein-1
Mice lacking aryl hydrocarbon (dioxin) receptor (AhR) had variable degree of hepatic fibrosis and altered liver architecture. Transforming growth factor-β (TGF-β), a major profibrogenic molecule in the liver, is localized to the extracellular matrix by its association to the latent TGF-β-binding pro...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517523/ https://ncbi.nlm.nih.gov/pubmed/15379962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0959-9673.2004.00397.x |
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