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Hyperproduction of fibrin and inefficacy of antithrombin III and α2 macroglobulin in the presence of bacterial porins

Bacterial porins enhance the thrombin activity upon chromogen substrate chromozym. Should porin-dependent enhancement of thrombin activity take place also upon fibrinogen in vivo, this might greatly increase the fibrin production which, in turn, might lead to blood vessel obstruction. In this study,...

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Autors principals: Di Micco, Biagio, Di Micco, Pierpaolo, Lepretti, Marilena, Stiuso, Paola, Donnarumma, Giovanna, Iovene, Maria R, Capasso, Rita, Tufano, Maria A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517434/
https://ncbi.nlm.nih.gov/pubmed/16045546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0959-9673.2005.00430.x
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