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SV-IV Peptide1–16 reduces coagulant power in normal Factor V and Factor V Leiden

Native Factor V is an anticoagulant, but when activated by thrombin, Factor X or platelet proteases, it becomes a procoagulant. Due to these double properties, Factor V plays a crucial role in the regulation of coagulation/anticoagulation balance. Factor V Leiden (FVL) disorder may lead to thromboph...

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Библиографические подробности
Главные авторы: Di Micco, Biagio, Lepretti, Marilena, Rota, Lidia, Quaglia, Ilaria, Ferrazzi, Paola, Di Micco, Gianluca, Di Micco, Pierpaolo
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241586/
https://ncbi.nlm.nih.gov/pubmed/18154667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-5-69
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