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An Antithrombin-Heparin Complex Increases the Anticoagulant Activity of Fibrin Clots

Clotting blood contains fibrin-bound thrombin, which is a major source of procoagulant activity leading to clot extension and further activation of coagulation. When bound to fibrin, thrombin is protected from inhibition by antithrombin (AT) + heparin but is neutralized when AT and heparin are coval...

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Detalhes bibliográficos
Main Authors: Smith, Lesley J., Mewhort-Buist, Tracy Anne, Berry, Leslie R., Chan, Anthony K. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005802/
https://ncbi.nlm.nih.gov/pubmed/22820671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/639829
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