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Inhibition of the prothrombinase complex on red blood cells by heparin and covalent antithrombin–heparin complex

The role of red blood cells (RBCs) in coagulation is not well understood. Overt exposure of phosphatidylserine on surfaces of RBCs provide docking sites for formation of the prothrombinase complex, which further aids in amplification of coagulation leading to subsequent thrombosis. No studies to dat...

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Hlavní autoři: Stevic, Ivan, Chan, Howard H.W., Berry, Leslie R., Chander, Ankush, Chan, Anthony K.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528004/
https://ncbi.nlm.nih.gov/pubmed/23100269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvs129
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