High risk acute lymphoblastic leukemia cells with bcr-abl and INK4A/ARF mutations retain susceptibility to alloreactive T cells

INK4A/ARF mutations are acquired in bcr/abl+ lymphoid blast phase chronic myelogenous leukemia (CML) and bcr/abl+ acute lymphoblastic leukemia (ALL). Donor lymphocyte infusion and graft versus leukemia are generally ineffective in such ALL’s, while GVL is highly active against bcr/abl+ CML that does...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Young, Faith M., Campbell, Andrew, Emo, Kris Lambert, Jansson, Johan, Wang, Pin-Yi, Jordan, Craig T., Mullen, Craig A.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517424/
https://ncbi.nlm.nih.gov/pubmed/18489987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2008.02.015
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki