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High risk acute lymphoblastic leukemia cells with bcr-abl and INK4A/ARF mutations retain susceptibility to alloreactive T cells
INK4A/ARF mutations are acquired in bcr/abl+ lymphoid blast phase chronic myelogenous leukemia (CML) and bcr/abl+ acute lymphoblastic leukemia (ALL). Donor lymphocyte infusion and graft versus leukemia are generally ineffective in such ALL’s, while GVL is highly active against bcr/abl+ CML that does...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517424/ https://ncbi.nlm.nih.gov/pubmed/18489987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2008.02.015 |
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