TGFβ1 induces epithelial–mesenchymal transition, but not myofibroblast transdifferentiation of human kidney tubular epithelial cells in primary culture

The origin and fate of renal interstitial myofibroblasts (MFs), the effector cells of renal fibrosis, are still debated. Experimental evidence suggests that renal MFs derive from tubular epithelial cells throughout the epithelial–mesenchymal transition (EMT) process. Primary human tubular epithelial...

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Bibliographische Detailangaben
Hauptverfasser: Forino, Monica, Torregrossa, Rossella, Ceol, Monica, Murer, Luisa, Vella, Manuela Della, Prete, Dorella Del, D'Angelo, Angela, Anglani, Franca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2006
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517360/
https://ncbi.nlm.nih.gov/pubmed/16709228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2006.00479.x
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