TGFβ1 induces epithelial–mesenchymal transition, but not myofibroblast transdifferentiation of human kidney tubular epithelial cells in primary culture

The origin and fate of renal interstitial myofibroblasts (MFs), the effector cells of renal fibrosis, are still debated. Experimental evidence suggests that renal MFs derive from tubular epithelial cells throughout the epithelial–mesenchymal transition (EMT) process. Primary human tubular epithelial...

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Autori principali: Forino, Monica, Torregrossa, Rossella, Ceol, Monica, Murer, Luisa, Vella, Manuela Della, Prete, Dorella Del, D'Angelo, Angela, Anglani, Franca
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517360/
https://ncbi.nlm.nih.gov/pubmed/16709228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2006.00479.x
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