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Synthesis of C-15 Vindoline Analogues by Palladium-Catalyzed Cross-Coupling Reactions

Described are general protocols for the rapid construction of various C-15-substituted analogs of vindoline using palladium-catalyzed cross-coupling reactions. The required bromo- and iodovindolines were prepared in high yield by the reaction of vindoline with N-bromosuccinimide or N-iodosuccinimide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Peter D., Sohn, Jeong-Hun, Rawal, Viresh H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517232/
https://ncbi.nlm.nih.gov/pubmed/16995709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo061243y
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