Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun,

The organophosphorus nerve agents sarin, soman, tabun, and VX exert their toxic effects by inhibiting the action of human acetylcholinesterase, a member of the serine hydrolase superfamily of enzymes. The current treatments for nerve agent exposure must be administered quickly to be effective and th...

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Bibliografski detalji
Glavni autori: Fleming, Christopher D., Edwards, Carol C., Kirby, Stephen D., Maxwell, Donald M., Potter, Philip M., Cerasoli, Douglas M., Redinbo, Matthew R.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517171/
https://ncbi.nlm.nih.gov/pubmed/17407327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700246n
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