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A Feature-Based Approach to Modeling Protein–DNA Interactions
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position specific scoring matrix (PSSM), which assumes independence between binding positions. However, in many cases, this simplify...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516605/ https://ncbi.nlm.nih.gov/pubmed/18725950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000154 |
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